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@@ -11,7 +11,7 @@ RecMpox is a command-line tool that **flags potential recombination events** in
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3. **Consensus genome classification**: Your consensus genomes are aligned to the same references. At each diagnostic SNP, the base is classified as matching reference 1, reference 2, or other (e.g., gaps or ambiguous bases).
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4. **Flagging potential recombinants**: If both references contribute at least 10% of the diagnostic positions in a genome, RecMpox flags it as a potential recombinant, since no single lineage clearly dominates.
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5. **Recombination tracts and breakpoints**: By examining the pattern of reference matches along the genome, RecMpox infers recombination tracts and identifies their breakpoints (start and end positions). By default, no consecutive-SNP filtering is applied (minimum run length = 1), but you can ignore single-SNP runs by adding `-breakpoint-snp` (or `-b`), which sets the minimum run length to 2.
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6 **Outputs**:
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6. **Outputs**:
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- TSV file: or each genome, reports the number and proportion of diagnostic SNPs matching each reference, the resulting recombinant flag, and summary statistics used for tract inference.
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- Interactive HTML report: Provides sortable tables, summary plots, per-sample visualisations, and genome-wide displays of inferred recombination tracts and breakpoints.
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- Aligned FASTA: Contains the aligned reference and query sequences used for analysis.
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## Support
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If you encounter any problems or have questions, please open an issue on GitHub.
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If you encounter any problems or have questions, please open an issue on GitHub.

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