.

Author: DaanJansen94

README.md

@@ -4,6 +4,13 @@ Virasign (**Viral** Read **ASSIGN**ment) is a viral taxonomic classification and
 
 Virasign has been validated to classify the diversity of human pathogens well. However, when extended to other sources such as viral diversity within animal hosts, there may not be sufficient references in the databases to find good hits using this approach. In such cases, you can specify your own custom databases or accessions to improve detection.
 
+### Why Virasign?
+
+- **Ease of use**: Single command (`virasign -i input_dir`). Default databases (RVDB, RefSeq) are built in (no separate download), and you can run with minimal setup.
+- **Clear output**: Results are easy to find and use (JSON summaries, per-reference FASTA/BAM/FASTQ), so you can move straight to consensus building or other preferred metagenomics pipeline steps.
+- **Visualization**: Interactive HTML reports with filterable tables, charts, and heatmaps give an immediate, interpretable overview of viral species, coverage, and identity without extra scripting.
+- **Blinding options**: You can blind specific viral species from all outputs (e.g. HIV, Hepatitis viruses, HTLV, EBV, CMV, HPV) so incidental findings do not appear in any files—useful for consent guidelines and ethical research practice.
+
 ## Installation
 
 ### 1. Create Conda Environment with Required Tools